Sam has finally reached the Great Pyramid. He must clear all the way to the Pyramid, get inside, and get beamed up by the Sirian spaceship. But, there is an unexpected surprise waiting for him: Ugh-Zan III. After killing him, Sam gets beamed up on the spaceship, gives a phone call to Mental, taunting him that he's coming to kill him, but it turns out that Mental is not at home right now so he leaves him a voice message, and leaves for Sirius, or so he thinks.
(HD-only) In the arena, from the middle tunnel on the left, after the Major Bio-mechanoid bursts through it, enter it to find a Large Health. You don't need to do this the moment they burst through the tunnels, but it's suggested you do it after all the fights in the arena are complete.