The Wolfinator is a bipedal creature with a wolf's head. Presumably, it is responsible for Serious Sam being teleported to Ancient Rome after defeating the Sirian Sphinx. It is found in Caesar's Palace, the last level in the game.
It has two attacks; fire an electric orb and summon Gunrillas after a certain amount of time has passed. The electric orb will split into three orbs when it reaches the middle of the room.
- The Wolfinator behaves nearly exactly the same as the Sirian Sphinx. It has the same Electric Orb attack and will summon enemies after a while. The only difference is that it summons Gunrillas instead of Cyclopses.
- The Uni-Directional Microwave Transmitter is very useful when fighting the Wolfinator. One shot will kill all of the Gunrillas it summons, making it simple clearing them out in order to start attacking the Wolfinator again. However, the UMT does no damage to the Wolfinator.
- As with the Sirian Sphinx, the Minigun and Rocket Launcher work best against the Wolfinator. The Minigun can quickly do a lot of damage to the Wolfinator that's due to its high rate of fire and decent damage per bullet, while the Rocket Launcher does less damage, but its decent ammo reserve and damage per shot will allow the player to finish off the Wolfinator if they run out of Minigun Bullets.